CNGB3 Antibody

CATALOG NUMBER: 56-597

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This CNGB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-55 amino acids from the N-terminal region of human CNGB3.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
92 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CNGB3
Additional Names:
Cyclic nucleotide-gated cation channel beta-3, Cone photoreceptor cGMP-gated channel subunit beta, Cyclic nucleotide-gated cation channel modulatory subunit, Cyclic nucleotide-gated channel beta-3, CNG channel beta-3, CNGB3
Protein Accession Number:
Q9NQW8
Protein Gi Number:
311033366
Ncbi Gene Id Number:
54714
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes the beta subunit of a cyclicnucleotide-gated ion channel. The encoded beta subunit appears toplay a role in modulation of channel function in conephotoreceptors. This heterotetrameric channel is necessary forsensory transduction, and mutations in this gene have beenassociated with achromatopsia 3, progressive cone dystrophy, andjuvenile macular degeneration, also known as Stargardt Disease.
Background Reference 1:
Komaromy, A.M., et al. Hum. Mol. Genet. 19(13):2581-2593(2010)
Background Reference 2:
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 3:
Thiadens, A.A., et al. Ophthalmology 117(4):825-830(2010)
Background Reference 4:
Azam, M., et al. Mol. Vis. 16, 774-781 (2010) :

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

56-597

List Size:
400 ul

List Price:

$495.00

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