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Western blot analysis in Jurkat cell line lysates (35ug/lane).
Western blot analysis in Jurkat cell line lysates (35ug/lane).

CNOT2 Antibody

CATALOG NUMBER: 57-581

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This CNOT2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 272-301 amino acids from the Central region of human CNOT2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
60 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CNOT2
Additional Names:
CCR4-NOT transcription complex subunit 2, CCR4-associated factor 2, CNOT2, CDC36, NOT2
Protein Accession Number:
Q9NZN8
Protein Gi Number:
46396017
Ncbi Gene Id Number:
4848
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a subunit of the multi-componentCCR4-NOT complex. The CCR4-NOT complex regulates mRNA synthesis anddegradation and is also thought to be involved in mRNA splicing,transport and localization. The encoded protein interacts withhistone deacetylases and functions as a repressor of polymerase IItranscription. Alternatively spliced transcript variants have beenobserved for this gene.
Background Reference 1:
Lau, N.C., et al. Biochem. J. 422(3):443-453(2009)
Background Reference 2:
Miyasaka, T., et al. Cancer Sci. 99(4):755-761(2008)
Background Reference 3:
Morita, M., et al. Mol. Cell. Biol. 27(13):4980-4990(2007)
Background Reference 4:
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-581

List Size:
400 ul

List Price:

$495.00

Datasheet
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