CNTF Recombinant Protein

CATALOG NUMBER: 40-510

Specifications
source-species:
E. coli
Species:
Rat
source-species:
E. coli
Recombinant Protein Sequence:
AFAEQTPLTL HRRDLCSRSI WLARKIRSDL TALMESYVKH QGLNKNINLD SVDGVPVAST DRWSEMTEAE RLQENLQAYR TFQGMLTKLL EDQRVHFTPT EGDFHQAIHT LMLQVSAFAY QLEELMVLLE QKIPENEADG MPATVGDGGL FEKKLWGLKV LQELSQWTVR SIHDLRVISS HQMGISALES HYGAKDKQM
Biological Activity:
Biological activity was determined by its ability to stimulate proliferation of human TF - 1 cells using a concentration range of 25.0 - 35.0 ng/mL.
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).
physical-state:
Lyophilized
Storage Conditions:
The lyophilized CNTF recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted CNTF is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing CNTF recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Ncbi Official Symbol:
Cntf
Additional Names:
Ciliary neurotrophic factor, CNTF
Protein Accession Number:
NP_037298.1
Protein Gi Number:
6978675
Ncbi Gene Id Number:
25707
Background:
CNTF is a potent neural factor that was originally characterized as a vital factor for the survival of chick ciliary neurons in vitro. CNTF is also important for the survival of other neural cell types including primary sensory neurons, motor neurons, basal forebrain neurons and type 2 astrocytes. CNTF is highly conserved across species and exhibits cross-species bioactivity. Recombinant rat CNTF is synthesized as a 199 amino acid polypeptide (22.7 kDa) lacking a hydrophobic N-terminal signal for secretion.

FOR RESEARCH USE ONLY

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Disclaimer:
This product is for research use only.

CATALOG NUMBER:

40-510

List Size:
0.005 mg, 0.025 mg

List Price:

Price range: $215.00 through $323.00

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