CNTFR alpha Recombinant Protein

CATALOG NUMBER: 96-194

Tested Applications:
WB
Specifications
source-species:
HEK293 cells
Species:
Human
source-species:
HEK293 cells
Recombinant Protein Sequence:
Gln 23 - Pro 346
Fusion Tag:
His Tag
Tested Applications:
WB
Application Note:
This recombinant protein can be used for WB. For research use only.
Predicted Molecular Weight:
36.9 kDa
Biological Activity:
Measured by its binding ability in a functional ELISA. Immobilized human CTNFR at 10μg/ml (100μl/well) can bind biotinylated human CNTF with a linear ranger of 3. 2 - 100 ng/mL.
Purity:
>95% as determined by SDS-PAGE.
physical-state:
Lyophilized
Buffer:
PBS, pH7.4
Storage Conditions:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Ncbi Official Symbol:
CNTFR
Additional Names:
CNTFR, CNTF R alpha
Protein Accession Number:
AAH01492
Ncbi Gene Id Number:
1271
Background:
Ciliary neurotrophic factor receptor subunit alpha (CNTFR or CNTFR-alpha) belongs to the type I cytokine receptor family and type 3 subfamily. CNTFR contains two fibronectin type-III domains and one Ig-like C2-type (immunoglobulin-like) domain. This receptor and its cognate ligand support the survival of neurons. This receptor is most closely related to the interleukin-6 receptor. This receptor possesses an unusual attachment to the cell membrane through a glycophosphatidylinositol linkage.
Background Reference 1:
Davis S., et al., 1991, Science 253 (5015): 59–63.
Background Reference 2:
Sleeman MW., et al., 2000, Pharm Acta Helv 74 (2–3): 265–72.

FOR RESEARCH USE ONLY

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Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

96-194

List Size:
0.1 mg

List Price:

$495.00

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