COL4A6 Antibody

CATALOG NUMBER: 59-095

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This COL4A6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 830-859 amino acids from the Central region of human COL4A6.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
164 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
COL4A6
Additional Names:
Collagen alpha-6(IV) chain, COL4A6
Protein Accession Number:
Q14031
Protein Gi Number:
116241307
Ncbi Gene Id Number:
1288
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes one of the six subunits of type IVcollagen, the major structural component of basement membranes.Like the other members of the type IV collagen gene family, thisgene is organized in a head-to-head conformation with another typeIV collagen gene, alpha 5 type IV collagen, so that the gene pairshares a common promoter. Deletions in the alpha 5 gene that extendinto the alpha 6 gene result in diffuse leiomyomatosis accompanyingthe X-linked Alport syndrome caused by the deletion in the alpha 5gene. Two splice variants have been identified for this gene.
Background Reference 1:
Romero, R., et al. Am. J. Obstet. Gynecol. (2010) In press :
Background Reference 2:
Bailey, S.D., et al. Diabetes Care (2010) In press :
Background Reference 3:
Romero, R., et al. Am. J. Obstet. Gynecol. 202 (5), 431 (2010) :
Background Reference 4:
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-095

List Size:
400 ul

List Price:

$495.00

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