COL6A2 Antibody

CATALOG NUMBER: 58-453

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This COL6A2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 719-747 amino acids from the C-terminal region of human COL6A2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
109 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
COL6A2
Additional Names:
Collagen alpha-2(VI) chain, COL6A2
Protein Accession Number:
P12110
Protein Gi Number:
125987812
Ncbi Gene Id Number:
1292
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
COL6A2 is one of the three alpha chains of type VIcollagen, a beaded filament collagen found in most connectivetissues. The product of this gene contains several domains similarto von Willebrand Factor type A domains. These domains have beenshown to bind extracellular matrix proteins, an interaction thatexplains the importance of this collagen in organizing matrixcomponents. Mutations in this gene are associated with Bethlemmyopathy and Ullrich scleroatonic muscular dystrophy. Threetranscript variants have been identified for this gene. [providedby RefSeq].
Background Reference 1:
Zhang, R.Z., et al. J. Biol. Chem. 285(13):10005-10015(2010)
Background Reference 2:
Bovolenta, M., et al. BMC Med. Genet. 11, 44 (2010) :
Background Reference 3:
Chapuis, J., et al. Mol. Psychiatry 14(11):1004-1016(2009)
Background Reference 4:
Freise, C., et al. Matrix Biol. 28(8):480-489(2009)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-453

List Size:
400 ul

List Price:

$495.00

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