COLQ Antibody

CATALOG NUMBER: 60-634

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Homology:
Predicted species reactivity based on immunogen sequence: Rat
Immunogen:
This COLQ antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 324-353 amino acids from the C-terminal region of human COLQ.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
48 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
COLQ
Additional Names:
Acetylcholinesterase collagenic tail peptide, AChE Q subunit, Acetylcholinesterase-associated collagen, COLQ
Protein Accession Number:
Q9Y215
Protein Gi Number:
116241309
Ncbi Gene Id Number:
8292
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes the subunit of a collagen-like moleculeassociated with acetylcholinesterase in skeletal muscle. Eachmolecule is composed of three identical subunits. Each subunitcontains a proline-rich attachment domain (PRAD) that binds anacetylcholinesterase tetramer to anchor the catalytic subunit ofthe enzyme to the basal lamina. Mutations in this gene areassociated with endplate acetylcholinesterase deficiency. Multipletranscript variants encoding different isoforms have been found forthis gene.
Background Reference 1:
Mihaylova, V., et al. Brain 131 (PT 3), 747-759 (2008) :
Background Reference 2:
Schreiner, F., et al. Neuromuscul. Disord. 17(3):262-265(2007)
Background Reference 3:
Ting, A.K., et al. Chem. Biol. Interact. 157-158, 63-70 (2005) :
Background Reference 4:
Dvir, H., et al. EMBO J. 23(22):4394-4405(2004)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-634

List Size:
400 ul

List Price:

$495.00

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