Connexin 43 (phospho Ser265) Antibody

CATALOG NUMBER: 79-878

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Connexin 43 (phospho Ser265) antibody was raised against a peptide sequence around phosphorylation site of Serine 265 (Q-K-Y (p)-A-Y) derived from Human Connexin 43.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Western Blot: 1:500~1:1000
Specificity:
Connexin 43 antibody detects endogenous levels of Connexin 43 only when phosphorylated at Serine 265
Predicted Molecular Weight:
43 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Isotype:
IgG
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
GJA1
Additional Names:
CX43, CXA1, CXN-43, GJA1
Protein Accession Number:
NP_000156.1
Protein Gi Number:
4504001
Ncbi Gene Id Number:
2697
Background:
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph.
Background Reference 1:
Toshihiko Toyofuku, J. Biol. Chem., May 1998; 273: 12725.
Background Reference 2:
Toshihiko Toyofuku, J. Biol. Chem., Jan 1998; 273: 1519.
Background Reference 3:
Masayuki Shimada, Biol Reprod, Apr 2001; 64: 1255.
Background Reference 4:
Merry L. Lindsey, Circulation, Jun 2006; 113: 2919 - 2928.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-878

List Size:
0.1 mg

List Price:

$376.00

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