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Western blot analysis of anti-GJA8 Antibody in HepG2 cell line lysates (35ug/lane)
Western blot analysis of anti-GJA8 Antibody in HepG2 cell line lysates (35ug/lane)

Connexin 50 Antibody

CATALOG NUMBER: 58-183

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This Connexin 50 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 99-130 amino acids from the N-terminal region of human Connexin 50.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
48 kDa
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
GJA8
Additional Names:
Gap junction alpha-8 protein, Connexin-50, Cx50, Lens fiber protein MP70, GJA8
Protein Accession Number:
P48165
Protein Gi Number:
13124697
Ncbi Gene Id Number:
2703
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
GJA8 is a an integral membrane protein that belongs to the connexin family, alpha-type (group II) subfamily. One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. A connexon is composed of a hexamer of connexins. This particular connexin only forms junctional channels. GJA8 is expressed in the eye lens, and defects in GJA8 are the cause of zonular pulverulent cataract type 1 (CZP1), a form of autosomal dominant congenital cataract.
Background Reference 1:
Shiels, A., et al., Am. J. Hum. Genet. 62(3):526-532 (1998).
Background Reference 2:
Church, R.L., et al., Curr. Eye Res. 14(10):979-981 (1995).
Background Reference 3:
Church, R.L., et al., Curr. Eye Res. 14(3):215-221 (1995).

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-183

List Size:
400 ul

List Price:

$495.00

Datasheet
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