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Western blot analysis in CEM cell line lysates (35ug/lane).
Western blot analysis in CEM cell line lysates (35ug/lane).

CORO2A Antibody

CATALOG NUMBER: 57-143

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This CORO2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 185-213 amino acids from the Central region of human CORO2A.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
60 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CORO2A
Additional Names:
Coronin-2A, IR10, WD repeat-containing protein 2, CORO2A, IR10, WDR2
Protein Accession Number:
Q92828
Protein Gi Number:
28381354
Ncbi Gene Id Number:
7464
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a member of the WD repeat proteinfamily. WD repeats are minimally conserved regions of approximately40 amino acids typically bracketed by gly-his and trp-asp (GH-WD),which may facilitate formation of heterotrimeric or multiproteincomplexes. Members of this family are involved in a variety ofcellular processes, including cell cycle progression, signaltransduction, apoptosis, and gene regulation. This protein contains5 WD repeats, and has a structural similarity with actin-bindingproteins: the D. discoideum coronin and the human p57 protein,suggesting that this protein may also be an actin-binding proteinthat regulates cell motility. Alternative splicing of this genegenerates 2 transcript variants.
Background Reference 1:
Jin, Y., et al. Nat. Genet. 42(7):576-578(2010)
Background Reference 2:
Marshall, T.W., et al. J. Cell. Sci. 122 (PT 17), 3061-3069 (2009) :
Background Reference 3:
Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)
Background Reference 4:
Yoon, H.G., et al. Mol. Cell 12(3):723-734(2003)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-143

List Size:
400 ul

List Price:

$495.00

Datasheet
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