COX5A Antibody

CATALOG NUMBER: 56-887

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Mouse
Immunogen:
This COX5A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-55 amino acids from the N-terminal region of human COX5A.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
17 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
COX5A
Additional Names:
Cytochrome c oxidase subunit 5A, mitochondrial, Cytochrome c oxidase polypeptide Va, COX5A
Protein Accession Number:
P20674
Protein Gi Number:
218511986
Ncbi Gene Id Number:
9377
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Cytochrome c oxidase (COX) is the terminal enzyme of themitochondrial respiratory chain. It is a multi-subunit enzymecomplex that couples the transfer of electrons from cytochrome c tomolecular oxygen and contributes to a proton electrochemicalgradient across the inner mitochondrial membrane. The complexconsists of 13 mitochondrial- and nuclear-encoded subunits. Themitochondrially-encoded subunits perform the electron transfer ofproton pumping activities. The functions of the nuclear-encodedsubunits are unknown but they may play a role in the regulation andassembly of the complex. This gene encodes the nuclear-encodedsubunit Va of the human mitochondrial respiratory chain enzyme. Apseudogene COX5AP1 has been found in chromosome 14q22. [provided byRefSeq].
Background Reference 1:
Chen, Z.X., et al. Cell Death Differ. 17(3):408-420(2010)
Background Reference 2:
Fornuskova, D., et al. Biochem. J. 428(3):363-374(2010)
Background Reference 3:
Uddin, M., et al. BMC Evol. Biol. 8,(2008) :
Background Reference 4:
Williams, S.L., et al. J. Biol. Chem. 279(9):7462-7469(2004)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

56-887

List Size:
400 ul

List Price:

$495.00

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