COX5B Antibody

Background:

Cytochrome C oxidase (COX) is the terminal enzyme of themitochondrial respiratory chain. It is a multi-subunit enzymecomplex that couples the transfer of electrons from cytochrome c tomolecular oxygen and contributes to a proton electrochemicalgradient across the inner mitochondrial membrane. The complexconsists of 13 mitochondrial- and nuclear-encoded subunits. Themitochondrially-encoded subunits perform the electron transfer andproton pumping activities. The functions of the nuclear-encodedsubunits are unknown but they may play a role in the regulation andassembly of the complex. This gene encodes the nuclear-encodedsubunit Vb of the human mitochondrial respiratory chain enzyme.