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Western blot analysis in Hela cell line lysates (35ug/lane).
Western blot analysis in Hela cell line lysates (35ug/lane).

CPS1 Antibody

CATALOG NUMBER: 58-231

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This CPS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 262-291 amino acids from the N-terminal region of human CPS1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
165 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CPS1
Additional Names:
Carbamoyl-phosphate synthase [ammonia], mitochondrial, Carbamoyl-phosphate synthetase I, CPSase I, CPS1
Protein Accession Number:
P31327
Protein Gi Number:
4033707
Ncbi Gene Id Number:
1373
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The mitochondrial enzyme encoded by this gene catalyzessynthesis of carbamoyl phosphate from ammonia and bicarbonate. Thisreaction is the first committed step of the urea cycle, which isimportant in the removal of excess urea from cells. The encodedprotein may also represent a core mitochondrial nucleoid protein.Three transcript variants encoding different isoforms have beenfound for this gene. The shortest isoform may not be localized tothe mitochondrion. Mutations in this gene have been associated withcarbamoyl phosphate synthetase deficiency, susceptibility topersistent pulmonary hypertension, and susceptibility tovenoocclusive disease after bone marrow transplantation.
Background Reference 1:
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Background Reference 2:
Jia, P., et al. Schizophr. Res. 122 (1-3), 38-42 (2010) :
Background Reference 3:
Pekkala, S., et al. Hum. Mutat. 31(7):801-808(2010)
Background Reference 4:
Huo, R., et al. J. Biochem. Mol. Biol. 38(1):28-33(2005)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-231

List Size:
400 ul

List Price:

$495.00

Datasheet
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