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Western blot analysis in A375 cell line lysates (35ug/lane).
Western blot analysis in A375 cell line lysates (35ug/lane).

CPSF3 Antibody

CATALOG NUMBER: 58-002

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Immunogen:
This CPSF3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 192-221 amino acids from the Central region of human CPSF3.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
77 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CPSF3
Additional Names:
Cleavage and polyadenylation specificity factor subunit 3, 3127-, Cleavage and polyadenylation specificity factor 73 kDa subunit, CPSF 73 kDa subunit, mRNA 3'-end-processing endonuclease CPSF-73, CPSF3, CPSF73
Protein Accession Number:
Q9UKF6
Protein Gi Number:
18203503
Ncbi Gene Id Number:
51692
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Most eukaryotic mRNA precursors (pre-mRNAs) undergoextensive maturational processing, including cleavage andpolyadenylation at the 3-prime end. CPSF3 encodes the 73-kD subunitof the cleavage and polyadenylation specificity factor (CPSF) andis the pre-mRNA 3-prime-end-processing endonuclease (Mandel et al.,2006 [PubMed 17128255]).
Background Reference 1:
Rozenblatt-Rosen, O., et al. Proc. Natl. Acad. Sci. U.S.A. 106(3):755-760(2009)
Background Reference 2:
Zhu, Z.H., et al. Oncogene 28(1):41-51(2009)
Background Reference 3:
Yang, X.C., et al. Mol. Cell. Biol. 29(1):31-42(2009)
Background Reference 4:
Kolev, N.G., et al. EMBO Rep. 9(10):1013-1018(2008)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-002

List Size:
400 ul

List Price:

$495.00

Datasheet
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