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Western blot analysis in K562 cell line lysates (35ug/lane).
CPSF3L Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
Confocal immunofluorescent analysis of CPSF3L Antibody with U-251MG cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
Western blot analysis in K562 cell line lysates (35ug/lane).

CPSF3L Antibody

CATALOG NUMBER: 55-677

Clonality:
Polyclonal
Tested Applications:
IF, IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Immunogen:
This CPSF3L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 91-119 amino acids from the N-terminal region of human CPSF3L.
Conjugate:
Unconjugated
Tested Applications:
IF, IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
For IF starting dilution is: 1:10~50
Predicted Molecular Weight:
68 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CPSF3L
Additional Names:
Integrator complex subunit 11, Int11, 3127-, Cleavage and polyadenylation-specific factor 3-like protein, CPSF3-like protein, Protein related to CPSF subunits of 68 kDa, RC-68, CPSF3L, INTS11, RC68
Protein Accession Number:
Q5TA45
Protein Gi Number:
118572557
Ncbi Gene Id Number:
54973
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The Integrator complex contains at least 12 subunits andassociates with the C-terminal domain of RNA polymerase II largesubunit (POLR2A; MIM 180660) and mediates the 3-prime endprocessing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2(RNU2; MIM 180690). INTS11, or CPSF3L, is the catalytic subunit ofthe Integrator complex (Baillat et al., 2005 [PubMed16239144]).
Background Reference 1:
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Background Reference 2:
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Background Reference 3:
Baillat, D., et al. Cell 123(2):265-276(2005)
Background Reference 4:
Dominski, Z., et al. Mol. Cell. Biol. 25(4):1489-1500(2005)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

55-677

List Size:
400 ul

List Price:

$495.00

Datasheet
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