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Western blot analysis in K562 cell line lysates (35ug/lane).
Western blot analysis in K562 cell line lysates (35ug/lane).

CPT1A Antibody

CATALOG NUMBER: 57-900

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This CPT1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 728-756 amino acids from the C-terminal region of human CPT1A.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
88 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CPT1A
Additional Names:
Carnitine O-palmitoyltransferase 1, liver isoform, CPT1-L, Carnitine O-palmitoyltransferase I, liver isoform, CPT I, CPTI-L, Carnitine palmitoyltransferase 1A, CPT1A, CPT1
Protein Accession Number:
P50416
Protein Gi Number:
56405343
Ncbi Gene Id Number:
1374
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The mitochondrial oxidation of long-chain fatty acids isinitiated by the sequential action of carnitinepalmitoyltransferase I (which is located in the outer membrane andis detergent-labile) and carnitine palmitoyltransferase II (whichis located in the inner membrane and is detergent-stable), togetherwith a carnitine-acylcarnitine translocase. CPT I is the key enzymein the carnitine-dependent transport across the mitochondrial innermembrane and its deficiency results in a decreased rate of fattyacid beta-oxidation. Alternatively spliced transcript variantsencoding different isoforms have been found for this gene.
Background Reference 1:
Gessner, B.D., et al. Pediatrics 126(5):945-951(2010)
Background Reference 2:
Collins, S.A., et al. Mol. Genet. Metab. 101 (2-3), 200-204 (2010) :
Background Reference 3:
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Background Reference 4:
Song, S., et al. Mol. Cell. Endocrinol. 325 (1-2), 54-63 (2010) :

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-900

List Size:
400 ul

List Price:

$495.00

Datasheet
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