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CREB-binding Protein highly active Recombinant Protein

CATALOG NUMBER: 90-344

Specifications
source-species:
Sf21 cells
Species:
Mouse
source-species:
Sf21 cells
Recombinant Protein Sequence:
Mouse CREB-binding protein fused at the C-terminus to a His-tag.
Fusion Tag:
His Tag
Application Note:
This recombinant proteins is for research use only.
Biological Activity:
~50-100ng are required for standard HAT assay.
Purity:
>95% (SDS-PAGE)
physical-state:
Liquid
Buffer:
In 50mM TRIS-HCl, pH 7.5, containing 100mM sodium chloride, 0.2% NP-40, 50-100mM imidazole and 10% glycerol.
Concentration:
Lot dependent (0.2-0.5mg/ml)
Storage Conditions:
Stable for at least 6 months after receipt when stored at -80°C.
Ncbi Official Symbol:
Crebbp
Additional Names:
CBP, CREBBP
Protein Accession Number:
P45481
Protein Gi Number:
341940549
Ncbi Gene Id Number:
12914
Background:
CREB-binding protein acetylates histones, giving a specific tag for transcriptional activation. It also acetylates non-histone proteins, like NCOA3 and FOXO1. It binds specifically to phosphorylated CREB and enhances its transcriptional activity toward cAMP-responsive genes. Acts as a coactivator of ALX1 in the presence of EP300.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

90-344

List Size:
2 ug

List Price:

$391.00

Datasheet
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