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Western blot analysis in Jurkat cell line lysates (35ug/lane).
Western blot analysis in Jurkat cell line lysates (35ug/lane).

CREB3 Antibody

CATALOG NUMBER: 60-832

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This CREB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-94 amino acids from the N-terminal region of human CREB3.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
44 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CREB3
Additional Names:
Cyclic AMP-responsive element-binding protein 3, CREB-3, cAMP-responsive element-binding protein 3, Leucine zipper protein, Luman, Transcription factor LZIP-alpha, Processed cyclic AMP-responsive element-binding protein 3, N-terminal Luman, Transcriptionally active form, CREB3, LZIP
Protein Accession Number:
O43889
Ncbi Gene Id Number:
10488
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a transcription factor that is a memberof the leucine zipper family of DNA binding proteins. This proteinbinds to the cAMP-response element and regulates cellproliferation. The protein interacts with host cell factor C1,which also associates with the herpes simplex virus (HSV) proteinVP16 that induces transcription of HSV immediate-early genes. Thisprotein and VP16 both bind to the same site on host cell factor C1.It is thought that the interaction between this protein and hostcell factor C1 plays a role in the establishment of latency duringHSV infection. This protein also plays a role in leukocytemigration, tumor suppression, and endoplasmic reticulumstress-associated protein degradation. Additional transcriptvariants have been identified, but their biological validity hasnot been determined.
Background Reference 1:
Kim, H.C., et al. Cell. Mol. Life Sci. 67(20):3499-3510(2010)
Background Reference 2:
Eleveld-Trancikova, D., et al. Mol. Immunol. 47 (11-12), 1963-1973 (2010) :
Background Reference 3:
Kang, H., et al. Mol. Endocrinol. 23(11):1746-1757(2009)
Background Reference 4:
Mamdani, F., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 147B (4), 500-504 (2008) :

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-832

List Size:
400 ul

List Price:

$495.00

Datasheet
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