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Antibody used in WB on Human Jurkat 1 ug/ml.
Antibody used in IHC on Human Breast at 5 ug/ml.
Antibody used in IHC on Human Colon at 5 ug/ml.
Antibody used in WB on Human Jurkat 1 ug/ml.

CREBBP Antibody

CATALOG NUMBER: 25-879

Clonality:
Polyclonal
Tested Applications:
ELISA, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CREBBP.
Conjugate:
Unconjugated
Tested Applications:
ELISA, WB
Application Note:
CREBBP antibody can be used for detection of CREBBP by ELISA at 1:312500. CREBBP antibody can be used for detection of CREBBP by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1205 - Jurkat Cell Lysate
Predicted Molecular Weight:
261 kDa
Purification:
Antibody is purified by peptide affinity chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store CREBBP antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
CREBBP
Additional Names:
CREBBP, CBP, KAT3A, RSTS, RTS
Protein Accession Number:
NP_001073315
Protein Gi Number:
119943102
Ncbi Gene Id Number:
1387
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
CREBBP is involved in the transcriptional coactivation of many different transcription factors. First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB), this gene is now known to play critical roles in embryonic development, growth control, and homeostasis by coupling chromatin remodeling to transcription factor recognition. CREBBP has intrinsic histone acetyltransferase activity and also acts as a scaffold to stabilize additional protein interactions with the transcription complex. This protein acetylates both histone and non-histone proteins. This protein shares regions of very high sequence similarity with protein p300 in its bromodomain, cysteine-histidine-rich regions, and histone acetyltransferase domain.
Background Reference 1:
Xia, Y., (2008) Biochem. Biophys. Res. Commun. 368 (2), 438-444.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

25-879

List Size:
100 ul

List Price:

$519.00

Datasheet
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