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Western blot analysis of extracts from HT-29 cells treated with heat shock using CRMP-2 (Phospho-Thr509) Antibody. The lane on the right is treated with the antigen-specific peptide.
Immunohistochemical analysis of paraffin-embedded human brain tissue using CRMP-2 (Phospho-Thr509) antibody (left) or the same antibody preincubated with blocking peptide (right).
Western blot analysis of extracts from HT-29 cells treated with heat shock using CRMP-2 (Phospho-Thr509) Antibody. The lane on the right is treated with the antigen-specific peptide.

CRMP-2 (phospho Thr509) Antibody

CATALOG NUMBER: 79-905

Clonality:
Polyclonal
Tested Applications:
IHC, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
CRMP-2 (phospho Thr509) antibody was raised against a peptide sequence around phosphorylation site of threonine 509 (S-V-T (p)-P-K) derived from Human CRMP-2.
Conjugate:
Unconjugated
Tested Applications:
IHC, WB
Application Note:
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Specificity:
The antibody detects endogenous levels of CRMP-2 only when phosphorylated at threonine 509.
Predicted Molecular Weight:
50 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Isotype:
IgG
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
DPYSL2
Additional Names:
CRMP2, N2A3, TOAD-64, DPYL2, ULIP2
Protein Accession Number:
NP_001377.1
Protein Gi Number:
3122051
Ncbi Gene Id Number:
1808
Background:
CRMP-2 is an enzyme with dihydropyrimidinase activity. Plays a role in RhoA-dependent signaling, through interaction with and regulation of Rho kinase. Plays a role in neurogenesis. Aberrantly expressed in fetal Down syndrome brain.
Background Reference 1:
Miki Y., Science 266:66-71(1994).
Background Reference 2:
Smith T.M., Genome Res. 6:1029-1049(1996).
Background Reference 3:
Wilson C.A., Oncogene 14:1-16(1997).

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-905

List Size:
0.1 mg

List Price:

$376.00

Datasheet
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