CRTAP Antibody

CATALOG NUMBER: 58-911

Clonality:
Polyclonal
Tested Applications:
IF, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This CRTAP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 31-59 amino acids from the N-terminal region of human CRTAP.
Conjugate:
Unconjugated
Tested Applications:
IF, WB
Application Note:
For IF starting dilution is: 1:25
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
47 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CRTAP
Additional Names:
Cartilage-associated protein, CRTAP, CASP
Protein Accession Number:
O75718
Ncbi Gene Id Number:
10491
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is similar to the chickenand mouse CRTAP genes. The encoded protein is a scaffolding proteinthat may influence the activity of at least one member of thecytohesin/ARNO family in response to specific cellular stimuli.Defects in this gene are associated with osteogenesis imperfecta, aconnective tissue disorder characterized by bone fragility and lowbone mass.
Background Reference 1:
Morello, R., et al. Curr Osteoporos Rep 8(2):77-83(2010)
Background Reference 2:
Li, G.H., et al. Osteoporos Int 21(6):1009-1020(2010)
Background Reference 3:
Fratzl-Zelman, N., et al. Bone 46(3):820-826(2010)
Background Reference 4:
Chang, W., et al. Hum. Mol. Genet. 19(2):223-234(2010)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-911

List Size:
400 ul

List Price:

$495.00

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