CRY1 Antibody

CATALOG NUMBER: 79-637

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Mouse
Immunogen:
CRY1 antibody was raised against a peptide sequence around aa.551~555 (S-Q-G-S-G) derived from Mouse CRY1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
Western Blot: 1:500~1:1000
Specificity:
This antibody detects endogenous level of total CRY1 protein.
Predicted Molecular Weight:
60 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
physical-state:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
Cry1
Additional Names:
Phll1, AU020726, AU021000, PHLL1
Protein Accession Number:
NP_031797.1
Protein Gi Number:
6681031
Ncbi Gene Id Number:
12952
Background:
Blue light-dependent regulator of the circadian feedback loop. Inhibits CLOCK, NPAS2-ARNTL E box-mediated transcription. Acts, in conjunction with CRY2, in maintaining period length and circadian rhythmicity. Has no photolyase activity. Capable of translocating circadian clock core proteins such as PER proteins to the nucleus. May inhibit CLOCK, NPAS2-ARNTL transcriptional activity through stabilizing the unphosphorylated form of ARNTL
Background Reference 1:
Morioka N, et al. (2010) J Pharmacol Sci. 113 (3): 234-45. Fonseca F, et al. (2010) Mol Diagn Ther. 14 (3): 171-8. Stratmann M, et al. (2010) Genes Dev. 24 (12): 1317-28.

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-637

List Size:
0.1 mg

List Price:

$370.00

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