CRYM Antibody

CATALOG NUMBER: 60-710

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Mouse
Immunogen:
This CRYM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 154-183 amino acids from the Central region of human CRYM.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
34 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CRYM
Additional Names:
Ketimine reductase mu-crystallin, NADP-regulated thyroid-hormone-binding protein, CRYM, THBP
Protein Accession Number:
Q14894
Protein Gi Number:
2498259
Ncbi Gene Id Number:
1428
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Crystallins are separated into two classes: taxon-specificand ubiquitous. The former class is also calledphylogenetically-restricted crystallins. The latter classconstitutes the major proteins of vertebrate eye lens and maintainsthe transparency and refractive index of the lens. This geneencodes a taxon-specific crystallin protein that binds NADPH andhas sequence similarity to bacterial ornithine cyclodeaminases. Theencoded protein does not perform a structural role in lens tissue,and instead it binds thyroid hormone for possible regulatory ordevelopmental roles. Mutations in this gene have been associatedwith autosomal dominant non-syndromic deafness. Multiplealternatively spliced transcript variants have been found for thisgene.
Background Reference 1:
Martins-de-Souza, D., et al.Psychiatr Res (2010) In press :
Background Reference 2:
Al-Kafaji, G., et al. Biochem. Biophys. Res. Commun. 391(4):1585-1591(2010)
Background Reference 3:
Malinowska, K., et al. Prostate 69(10):1109-1118(2009)
Background Reference 4:
Martins-de-Souza, D., et al.Psychiatr Res 43(11):978-986(2009)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-710

List Size:
400 ul

List Price:

$495.00

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