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Antibody used in IHC on Human kidney lysate.
Antibody used in WB on Human Jurkat 0.2-1 ug/ml.
Antibody used in IHC on Human kidney lysate.

CSEN Antibody

CATALOG NUMBER: 27-446

Clonality:
Polyclonal
Tested Applications:
ELISA, IHC, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CSEN.
Conjugate:
Unconjugated
Tested Applications:
ELISA, IHC, WB
Application Note:
CSEN antibody can be used for detection of CSEN by ELISA at 1:12500. CSEN antibody can be used for detection of CSEN by western blot at 2.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Positive Control 1:
Cat. No. 1205 - Jurkat Cell Lysate
Predicted Molecular Weight:
29 kDa
Purification:
Antibody is purified by peptide affinity chromatography method.
Clonality:
Polyclonal
Physical State:
Liquid
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Storage Conditions:
For short periods of storage (days) store at 4°C. For longer periods of storage, store CSEN antibody at -20°C. As with any antibody avoid repeat freeze-thaw cycles.
Ncbi Official Symbol:
KCNIP3
Additional Names:
CSEN, CSEN, DREAM, KCHIP3
Protein Accession Number:
NP_038462
Protein Gi Number:
7305199
Ncbi Gene Id Number:
30818
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
CSEN is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The protein encoded by this gene is also shown to function as a calcium-regulated transcriptional repressor, and to interact with presenilins. Mutations in the presenilin genes have been implicated in Alzheimer's disease.
Background Reference 1:
Zaidi, N.F., et al., (2004) J. Neurochem. 89 (3), 593-601.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

27-446

List Size:
100 ul

List Price:

$519.00

Datasheet
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