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Western blot analysis of extracts from HepG2 cells treated with PMA using CSFR (Phospho-Tyr561) Antibody. The lane on the right is treated with the antigen-specific peptide.
Immunohistochemical analysis of paraffin-embedded human brain, using CSFR (Phospho-Tyr561) antibody (left) or the same antibody preincubated with blocking peptide (right).
Western blot analysis of extracts from HepG2 cells treated with PMA using CSFR (Phospho-Tyr561) Antibody. The lane on the right is treated with the antigen-specific peptide.

CSFR (phospho Tyr561) Antibody

CATALOG NUMBER: 79-809

Clonality:
Polyclonal
Tested Applications:
IHC, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Immunogen:
CSFR (phospho Tyr561) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 561 (N-S-Y (p)-T-F) derived from Human CSFR .
Conjugate:
Unconjugated
Tested Applications:
IHC, WB
Application Note:
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Specificity:
The antibody detects endogenous levels of CSFR only when phosphorylated at tyrosine 561.
Predicted Molecular Weight:
130 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Isotype:
IgG
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
CSF1R
Additional Names:
CD115, CSF-1-R, CSFMR, FMS, M-CSFR
Protein Accession Number:
NP_001275634.1
Protein Gi Number:
27262659
Ncbi Gene Id Number:
1436
Background:
Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines in response to IL34 and CSF1, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone and tooth development.
Background Reference 1:
Hampe A., Oncogene Res. 4:9-17(1989).
Background Reference 2:
Andre C., Genomics 39:216-226(1997).
Background Reference 3:
Liu T., J. Proteome Res. 4:2070-2080(2005).

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-809

List Size:
0.1 mg

List Price:

$376.00

Datasheet
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