CSHL1 Antibody

CATALOG NUMBER: 56-820

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This CSHL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-185 amino acids from the C-terminal region of human CSHL1.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
25 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CSHL1
Additional Names:
Chorionic somatomammotropin hormone-like 1, Chorionic somatomammotropin-like, Lactogen-like, CSHL1, CSHP1, CSL
Protein Accession Number:
Q14406
Protein Gi Number:
313104096
Ncbi Gene Id Number:
1444
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is a member of thesomatotropin/prolactin family of hormones which play an importantrole in growth control. The gene, along with four other relatedgenes, is located at the growth hormone locus on chromosome 17where they are interspersed in the same transcriptionalorientation; an arrangement which is thought to have evolved by aseries of gene duplications. Although the five genes share aremarkably high degree of sequence identity, they are expressedselectively in different tissues. This particular family member isexpressed in placental villi, although it was originally thought tobe a pseudogene. In fact, alternative splicing suggests that themajority of the transcripts would be unable to express a secretedprotein. Alternatively spliced transcript variants encodingdifferent isoforms have been identified.
Background Reference 1:
Bailey, S.D., et al. Diabetes Care (2010) In press :
Background Reference 2:
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Background Reference 3:
Misra-Press, A., et al. J. Biol. Chem. 269(37):23220-23229(1994)
Background Reference 4:
MacLeod, J.N., et al. J. Biol. Chem. 267(20):14219-14226(1992)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

56-820

List Size:
400 ul

List Price:

$495.00

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