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Western blot analysis of extracts from Jurkat cells treated with TNF using CtBP1 (Phospho-Ser422) Antibody. The lane on the right is treated with the antigen-specific peptide.
Immunohistochemical analysis of paraffin-embedded human brain tissue, using CtBP1 (Phospho-Ser422) antibody (left) or the same antibody preincubated with blocking peptide (right).
Western blot analysis of extracts from Jurkat cells treated with TNF using CtBP1 (Phospho-Ser422) Antibody. The lane on the right is treated with the antigen-specific peptide.

CtBP1 (phospho Ser422) Antibody

CATALOG NUMBER: 79-906

Clonality:
Polyclonal
Tested Applications:
IHC, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
CtBP1 (phospho Ser422) antibody was raised against a peptide sequence around phosphorylation site of Serine 422 (A-P-S (p)-P-G) derived from Human CtBP1.
Conjugate:
Unconjugated
Tested Applications:
IHC, WB
Application Note:
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Specificity:
The antibody detects endogenous levels of CtBP1 only when phosphorylated at serine 422.
Predicted Molecular Weight:
48 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Isotype:
IgG
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
CTBP1
Additional Names:
CTBP, C-terminal binding protein 1, EC 1.1.1
Protein Accession Number:
NP_001319.1
Protein Gi Number:
4557497
Ncbi Gene Id Number:
1487
Background:
This gene encodes a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants.
Background Reference 1:
Schaeper U., Proc. Natl. Acad. Sci. U.S.A. 92:10467-10471(1995).
Background Reference 2:
Sewalt R.G.A.B., Mol. Cell. Biol. 19:777-787(1999).
Background Reference 3:
The MGC Project Team, Genome Res. 14:2121-2127(2004).

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-906

List Size:
0.1 mg

List Price:

$376.00

Datasheet
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