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CTGFL Recombinant Protein

CATALOG NUMBER: 40-215

Specifications
source-species:
E. coli
Species:
Human
source-species:
E. coli
Recombinant Protein Sequence:
MQLCPTPCTC PWPPPRCPLG VPLVLDGCGC CRVCARRLGE PCDQLHVCDA SQGLVCQPGA GPGGRGALCL LAEDDSSCEV NGRLYREGET FQPHCSIRCR CEDGGFTCVP LCSEDVRLPS WDCPHPRRVE VLGKCCPEWV CGQGGGLGTQ PLPAQGPQFS GLVSSLPPGV PCPEWSTAWG PCSTTCGLGM ATRVSNQNRF CRLETQRRLC LSRPCPPSRG RSPQNSAF
Biological Activity:
The ED50 was determined by its ability to inhibit IGF - II induced proliferation of MCF - 7 is between 10 - 20 ng/mL in the presence of 15 ng/mL of human IGF - II.
Purity:
Greater than 95% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).
physical-state:
Lyophilized
Storage Conditions:
The lyophilized CTGFL recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted CTGFL is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing CTGFL recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Ncbi Official Symbol:
WISP2
Additional Names:
CCN5, CT58, CTGF-L, CCN5, CTGFL, UNQ228/PRO261, WNT1-inducible-signaling pathway protein 2, CCN family member 5, WISP-2
Protein Accession Number:
NP_003872.1
Protein Gi Number:
4507923
Ncbi Gene Id Number:
8839
Background:
CTGFL/WISP-2 is a 24.3 kDa protein that belongs to the CCN family of cysteine rich regulatory proteins. Members of this family stimulate mitosis, adhesion, apoptosis, extracellular matrix production, growth arrest, and migration of multiple cell types. The protein is expressed in primary osteoblasts, fibroblasts, ovary, testes, and heart. In addition to promoting adhesion of osteoblasts, CTGFL/WISP-2 inhibits osteocalcin production, as well as binding of fibrinogen to integrin receptors. Recombinant human CTGFL/WISP-2 is a 24.3 kDa protein of 228 amino acid residues.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
This product is for research use only.

CATALOG NUMBER:

40-215

List Size:
0.005 mg, 0.02 mg

List Price:

Price range: $215.00 through $323.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

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