CTNS Antibody

CATALOG NUMBER: 60-528

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This CTNS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 341-367 amino acids from the C-terminal region of human CTNS.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
42 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CTNS
Additional Names:
Cystinosin, CTNS
Protein Accession Number:
O60931
Ncbi Gene Id Number:
1497
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a seven-transmembrane domain proteinthat functions to transport cystine out of lysosomes. Its activityis driven by the H+ electrochemical gradient of the lysosomalmembrane. Mutations in this gene cause cystinosis, a lysosomalstorage disorder. Alternative splicing results in multipletranscript variants.
Background Reference 1:
Taranta, A., et al. Pediatr. Nephrol. 25(7):1263-1267(2010)
Background Reference 2:
Bellomo, F., et al. Free Radic. Biol. Med. 48(7):865-872(2010)
Background Reference 3:
Kumar, A., et al. J. Biosci. 35(1):21-25(2010)
Background Reference 4:
Aldahmesh, M.A., et al. Ophthalmic Genet. 30(4):185-189(2009)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-528

List Size:
400 ul

List Price:

$495.00

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