CTSD Antibody

CATALOG NUMBER: 63-951

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This CTSD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 377-408 amino acids from the C-terminal region of human CTSD.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
45 kDa
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CTSD
Additional Names:
Cathepsin D, Cathepsin D light chain, Cathepsin D heavy chain, CTSD, CPSD
Protein Accession Number:
P07339
Protein Gi Number:
115717
Ncbi Gene Id Number:
1509
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
CTSD encodes a lysosomal aspartyl protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. This proteinase, which is a member of the peptidase C1 family, has a specificity similar to but narrower than that of pepsin A. Transcription of this gene is initiated from several sites, including one which is a start site for an estrogen-regulated transcript.
Background Reference 1:
Christensen, B., et al. J. Biol. Chem. 285(11):7929-7937(2010)
Background Reference 2:
Albayrak, O., et al. J. Gerontol.Biol. Sci. Med. Sci. 65(3):219-224(2010)
Background Reference 3:
Heinrich, M., et al. EMBO J. 18(19):5252-5263(1999)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

63-951

List Size:
400 ul

List Price:

$495.00

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