CXCL11 Antibody

CATALOG NUMBER: 58-013

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This CXCL11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 64-93 amino acids from the C-terminal region of human CXCL11.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
10 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CXCL11
Additional Names:
C-X-C motif chemokine 11, Beta-R1, H174, Interferon gamma-inducible protein 9, IP-9, Interferon-inducible T-cell alpha chemoattractant, I-TAC, Small-inducible cytokine B11, CXCL11, ITAC, SCYB11, SCYB9B
Protein Accession Number:
O14625
Ncbi Gene Id Number:
6373
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Chemokines are a group of small (approximately 8 to 14kD), mostly basic, structurally related molecules that regulatecell trafficking of various types of leukocytes throughinteractions with a subset of 7-transmembrane, G protein-coupledreceptors. Chemokines also play fundamental roles in thedevelopment, homeostasis, and function of the immune system, andthey have effects on cells of the central nervous system as well ason endothelial cells involved in angiogenesis or angiostasis.Chemokines are divided into 2 major subfamilies, CXC and CC. Thisgene is a CXC member of the chemokine superfamily. Its encodedprotein induces a chemotactic response in activated T-cells and isthe dominant ligand for CXC receptor-3. The gene encoding thisprotein contains 4 exons and at least three polyadenylation signalswhich might reflect cell-specific regulation of expression.IFN-gamma is a potent inducer of transcription of this gene.
Background Reference 1:
Rot, A. Front. Biosci. 15, 645-660 (2010) :
Background Reference 2:
Luttrell, L.M. Mol. Biotechnol. 39(3):239-264(2008)
Background Reference 3:
Kouroumalis, A., et al. J. Immunol. 175(8):5403-5411(2005)
Background Reference 4:
Booth, V., et al. Protein Sci. 13(8):2022-2028(2004)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-013

List Size:
400 ul

List Price:

$495.00

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