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Western blot analysis of anti-CYP1B1 Antibody in CEM cell line lysates (35ug/lane).
Western blot analysis of anti-CYP1B1 Antibody in CEM cell line lysates (35ug/lane).

CYP1B1 Antibody

CATALOG NUMBER: 63-271

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This CYP1B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 143-176 amino acids from the Central region of human CYP1B1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
61 kDa
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CYP1B1
Additional Names:
Cytochrome P450 1B1, CYPIB1, CYP1B1
Protein Accession Number:
Q16678
Protein Gi Number:
48429256
Ncbi Gene Id Number:
1545
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
CYP1B1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in CYP1B1 gene have been associated with primary congenital glaucoma; therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid.
Background Reference 1:
Suri,F., Mol. Vis. 14, 2349-2356 (2008)
Background Reference 2:
Nelson,D.R., Pharmacogenetics 14 (1), 1-18 (2004)
Background Reference 3:
Stoilov,I., Hum. Mol. Genet.(4), 641-647 (1997)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

63-271

List Size:
400 ul

List Price:

$495.00

Datasheet
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