CYP4A11 Antibody

CATALOG NUMBER: 63-267

Clonality:
Polyclonal
Tested Applications:
IF, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This CYP4A11 (4A22) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 407-435 amino acids from the C-terminal region of human CYP4A11 (4A22).
Conjugate:
Unconjugated
Tested Applications:
IF, WB
Application Note:
For WB starting dilution is: 1:1000
For IF starting dilution is: 1:10~50
Predicted Molecular Weight:
59 kDa
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CYP4A11
Additional Names:
Cytochrome P450 4A11, 20-hydroxyeicosatetraenoic acid synthase, 20-HETE synthase, CYP4AII, CYPIVA11, Cytochrome P-450HK-omega, Cytochrome P450HL-omega, Fatty acid omega-hydroxylase, Lauric acid omega-hydroxylase, CYP4A11, CYP4A2
Protein Accession Number:
Q02928
Protein Gi Number:
2493371
Ncbi Gene Id Number:
1579
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
CYP4A11 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates medium-chain fatty acids such as laurate and myristate.
Background Reference 1:
Sugimoto,K., Hypertension 52 (6), 1142-1148 (2008)
Background Reference 2:
Ward,N.C., Hypertension 51 (5), 1393-1398 (2008)
Background Reference 3:
Nelson,D.R., Pharmacogenetics 14 (1), 1-18 (2004)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

63-267

List Size:
400 ul

List Price:

$495.00

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