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Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).
CYSLTR1 Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human lung tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
Western blot analysis in ZR-75-1 cell line lysates (35ug/lane).

CYSLTR1 Antibody

CATALOG NUMBER: 58-011

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This CYSLTR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 144-172 amino acids from the Central region of human CYSLTR1.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
39 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CYSLTR1
Additional Names:
Cysteinyl leukotriene receptor 1, CysLTR1, Cysteinyl leukotriene D4 receptor, LTD4 receptor, G-protein coupled receptor HG55, HMTMF81, CYSLTR1, CYSLT1
Protein Accession Number:
Q9Y271
Protein Gi Number:
20138087
Ncbi Gene Id Number:
10800
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The cysteinyl leukotrienes LTC4, LTD4, and LTE4 areimportant mediators of human bronchial asthma. Pharmacologicstudies have determined that cysteinyl leukotrienes activate atleast 2 receptors, the protein encoded by this gene and CYSLTR2.This encoded receptor is a member of the superfamily of Gprotein-coupled receptors. Activation of this receptor by LTD4results in contraction and proliferation of smooth muscle, oedema,eosinophil migration and damage to the mucus layer in the lung.
Background Reference 1:
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Background Reference 2:
Boulay, M.E., et al. Prostaglandins Leukot. Essent. Fatty Acids 83(1):15-22(2010)
Background Reference 3:
Schuurhof, A., et al. Pediatr. Pulmonol. 45(6):608-613(2010)
Background Reference 4:
Hasegawa, S., et al. Platelets 21(4):253-259(2010)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-011

List Size:
400 ul

List Price:

$495.00

Datasheet
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