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Western blot analysis of CYTH3 Antibody in Hela cell line lysates (35ug/lane).
Western blot analysis of CYTH3 Antibody in mouse cerebellum tissue lysates (35ug/lane)
Western blot analysis of CYTH3 Antibody in Hela cell line lysates (35ug/lane).

CYTH3 Antibody

CATALOG NUMBER: 64-059

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse
Homology:
Predicted species reactivity based on immunogen sequence: Rat
Immunogen:
This CYTH3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 371-400 amino acids from the C-terminal region of human CYTH3.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
46 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
CYTH3
Additional Names:
Cytohesin-3, ARF nucleotide-binding site opener 3, Protein ARNO3, General receptor of phosphoinositides 1, Grp1, PH, SEC7 and coiled-coil domain-containing protein 3, CYTH3, ARNO3, GRP1, PSCD3
Protein Accession Number:
O43739
Ncbi Gene Id Number:
9265
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a member of the PSCD (pleckstrin homology, Sec7 and coiled-coil domains) family. PSCD family members have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This encoded protein is involved in the control of Golgi structure and function, and it may have a physiological role in regulating ADP-ribosylation factor protein 6 (ARF) functions, in addition to acting on ARF1.
Background Reference 1:
Morishige, M., et al. Nat. Cell Biol. 10(1):85-92(2008)
Background Reference 2:
Poirier, M.B., et al. Mol. Endocrinol. 19(8):1991-2005(2005)
Background Reference 3:
Nevrivy, D.J., et al. J. Biol. Chem. 275(22):16827-16836(2000)
Background Reference 4:
Ogasawara, M., et al. J. Biol. Chem. 275(5):3221-3230(2000)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

64-059

List Size:
400 ul

List Price:

$495.00

Datasheet
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