DACH2 Antibody

CATALOG NUMBER: 56-944

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen:
This DACH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-173 amino acids from the N-terminal region of human DACH2.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
65 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
DACH2
Additional Names:
Dachshund homolog 2, Dach2, DACH2
Protein Accession Number:
Q96NX9
Protein Gi Number:
44887818
Ncbi Gene Id Number:
117154
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene is one of two genes which encode a proteinsimilar to the Drosophila protein dachshund, a transcription factorinvolved in cell fate determination in the eye, limb and genitaldisc of the fly. The encoded protein contains two characteristicdachshund domains: an N-terminal domain responsible for DNA bindingand a C-terminal domain responsible for protein-proteininteractions. This gene is located on the X chromosome and issubject to inactivation by DNA methylation. The encoded protein maybe involved in regulation of organogenesis and myogenesis, and mayplay a role in premature ovarian failure. Multiple transcriptvariants encoding different isoforms have been found for this gene.
Background Reference 1:
Bailey, S.D., et al. Diabetes Care (2010) In press :
Background Reference 2:
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Background Reference 3:
Styrkarsdottir, U., et al. Nat. Genet. 41(1):15-17(2009)
Background Reference 4:
Poulin, F., et al. Genomics 85(6):774-781(2005)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

56-944

List Size:
400 ul

List Price:

$495.00

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