DAO Antibody

CATALOG NUMBER: 57-366

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This DAO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 259-287 amino acids from the Central region of human DAO.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
39 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
DAO
Additional Names:
D-amino-acid oxidase, DAAO, DAMOX, DAO, DAO, DAMOX
Protein Accession Number:
P14920
Protein Gi Number:
25453448
Ncbi Gene Id Number:
1610
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes the peroxisomal enzyme D-amino acidoxidase. The enzyme is a flavoprotein which uses flavin adeninedinucleotide (FAD) as its prosthetic group. Its substrates includea wide variety of D-amino acids, but it is inactive on thenaturally occurring L-amino acids. Its biological function is notknown; it may act as a detoxifying agent which removes D-aminoacids that accumulate during aging. In mice, it degrades D-serine,a co-agonist of the NMDA receptor. This gene may play a role in thepathophysiology of schizophrenia.
Background Reference 1:
Kim, B., et al. Psychiatry Res 179(2):121-125(2010)
Background Reference 2:
Caldinelli, L., et al. Protein Sci. 19(8):1500-1512(2010)
Background Reference 3:
Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)
Background Reference 4:
Ohnuma, T., et al. Schizophr. Res. 118 (1-3), 300-302 (2010) :

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-366

List Size:
400 ul

List Price:

$495.00

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