DDR1 (phospho Tyr513) Antibody

CATALOG NUMBER: 79-881

Clonality:
Polyclonal
Tested Applications:
IHC, WB
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human, Mouse, Rat
Immunogen:
DDR1 (phospho Tyr513) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 513 (K-K-Y (p)-V-R) derived from Human DDR1 .
Conjugate:
Unconjugated
Tested Applications:
IHC, WB
Application Note:
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Specificity:
The antibody detects endogenous levels of DDR1 only when phosphorylated at tyrosine 513.
Predicted Molecular Weight:
110 kDa
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Clonality:
Polyclonal
Isotype:
IgG
Physical State:
Liquid
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Storage Conditions:
Store antibody at -20°C for up to one year.
Ncbi Official Symbol:
DDR1
Additional Names:
CAK, RTK6, TRKE, EDDR1
Protein Accession Number:
NP_001189450.1
Protein Gi Number:
729008
Ncbi Gene Id Number:
780
Background:
Receptor tyrosine kinases (RTKs) play a key role in the communication of cells with their microenvironment. These molecules are involved in the regulation of cell growth, differentiation and metabolism. The protein encoded by this gene is a RTK that is widely expressed in normal and transformed epithelial cells and is activated by various types of collagen. This protein belongs to a subfamily of tyrosine kinase receptors with a homology region to the Dictyostelium discoideum protein discoidin I in their extracellular domain. Its autophosphorylation is achieved by all collagens so far tested (type I to type VI).
Background Reference 1:
di Marco E., J. Biol. Chem. 268:24290-24295(1993).
Background Reference 2:
Johnson J.D., Proc. Natl. Acad. Sci. U.S.A. 90:5677-5681(1993).
Background Reference 3:
Laval S., Cell Growth Differ. 5:1173-1183(1994).

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

79-881

List Size:
0.1 mg

List Price:

$376.00

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