DDX20 Antibody

CATALOG NUMBER: 58-056

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This DDX20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 713-741 amino acids from the C-terminal region of human DDX20.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
92 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
DDX20
Additional Names:
Probable ATP-dependent RNA helicase DDX20, Component of gems 3, DEAD box protein 20, DEAD box protein DP 103, Gemin-3, DDX20, DP103, GEMIN3
Protein Accession Number:
Q9UHI6
Protein Gi Number:
12643886
Ncbi Gene Id Number:
11218
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
DEAD box proteins, characterized by the conserved motifAsp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They areimplicated in a number of cellular processes involving alterationof RNA secondary structure such as translation initiation, nuclearand mitochondrial splicing, and ribosome and spliceosome assembly.Based on their distribution patterns, some members of this familyare believed to be involved in embryogenesis, spermatogenesis, andcellular growth and division. This gene encodes a DEAD box protein,which has an ATPase activity and is a component of the survival ofmotor neurons (SMN) complex. This protein interacts directly withSMN, the spinal muscular atrophy gene product, and may play acatalytic role in the function of the SMN complex on RNPs.
Background Reference 1:
Todd, A.G., et al. J. Mol. Biol. 401(5):681-689(2010)
Background Reference 2:
Sun, X., et al. Cell Stress Chaperones 15(5):567-582(2010)
Background Reference 3:
Wilker, E.H., et al. Environ. Health Perspect. 118(7):943-948(2010)
Background Reference 4:
Boni, V., et al. Pharmacogenomics J. (2010) In press :

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-056

List Size:
400 ul

List Price:

$495.00

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