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Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).
Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).

DEDD Antibody

CATALOG NUMBER: 59-960

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Immunogen:
This DEDD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 165-191 amino acids from the Central region of human DEDD.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
37 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
DEDD
Additional Names:
Death effector domain-containing protein, DEDPro1, Death effector domain-containing testicular molecule, FLDED-1, DEDD, DEDPRO1, DEFT
Protein Accession Number:
O75618
Ncbi Gene Id Number:
9191
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a protein that contains a death effectordomain (DED). DED is a protein-protein interaction domain shared byadaptors, regulators and executors of the programmed cell deathpathway. Overexpression of this gene was shown to induce weakapoptosis. Upon stimulation, this protein was found to translocatefrom cytoplasm to nucleus and colocalize with UBTF, a basal factorrequired for RNA polymerase I transcription, in the nucleolus. Atleast three transcript variants encoding the same protein have beenfound for this gene.
Background Reference 1:
Thorenoor, N., et al. Biochemistry 49(7):1435-1447(2010)
Background Reference 2:
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Background Reference 3:
Park, M.Y., et al. Int. J. Cancer 115(3):412-418(2005)
Background Reference 4:
Alcivar, A., et al. Oncogene 22(2):291-297(2003)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-960

List Size:
400 ul

List Price:

$495.00

Datasheet
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