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Western blot analysis in Jurkat cell line lysates (35ug/lane).
Western blot analysis in Jurkat cell line lysates (35ug/lane).

DEFA3 Antibody

CATALOG NUMBER: 60-421

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This DEFA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-65 amino acids from the C-terminal region of human DEFA3.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
10 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
DEFA3
Additional Names:
Neutrophil defensin 3, Defensin, alpha 3, HNP-3, HP-3, HP3, HP 3-56, Neutrophil defensin 2, HNP-2, HP-2, HP2, DEFA3, DEF3
Protein Accession Number:
P59666
Protein Gi Number:
30316323
Ncbi Gene Id Number:
1668
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Defensins are a family of microbicidal and cytotoxicpeptides thought to be involved in host defense. They are abundantin the granules of neutrophils and also found in the epithelia ofmucosal surfaces such as those of the intestine, respiratory tract,urinary tract, and vagina. Members of the defensin family arehighly similar in protein sequence and distinguished by a conservedcysteine motif. The protein encoded by this gene, defensin, alpha3, is found in the microbicidal granules of neutrophils and likelyplays a role in phagocyte-mediated host defense. Several alphadefensin genes are clustered on chromosome 8. This gene differsfrom defensin, alpha 1 by only one amino acid. This gene and thegene encoding defensin, alpha 1 are both subject to copy numbervariation.
Background Reference 1:
Han, S., et al. Hum. Immunol. 71(7):727-730(2010)
Background Reference 2:
Chen, Q., et al. Anesthesiology 112(6):1428-1434(2010)
Background Reference 3:
Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19(5):1356-1361(2010)
Background Reference 4:
Paslakis, G., et al. Nephron Exp. Nephrol. 115 (4), E96-E100 (2010) :

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

60-421

List Size:
400 ul

List Price:

$495.00

Datasheet
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