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Western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the DES antibody detected the DES protein (arrow).
DES/Desmin (Muscle Cell Marker) Antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of DES/Desmin (Muscle Cell Marker) Antibody for immunohistochemistry.
Western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the DES antibody detected the DES protein (arrow).

Desmin Antibody

CATALOG NUMBER: 57-618

Clonality:
Polyclonal
Tested Applications:
IHC-P, WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Pig, Rat
Immunogen:
This Desmin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 332-359 amino acids from the C-terminal region of human Desmin.
Conjugate:
Unconjugated
Tested Applications:
IHC-P, WB
Application Note:
For WB starting dilution is: 1:1000
For IHC-P starting dilution is: 1:10~50
Predicted Molecular Weight:
54 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
DES
Additional Names:
Desmin, DES
Protein Accession Number:
P17661
Protein Gi Number:
6686280
Ncbi Gene Id Number:
1674
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes a muscle-specific class III intermediatefilament. Homopolymers of this protein form a stableintracytoplasmic filamentous network connecting myofibrils to eachother and to the plasma membrane. Mutations in this gene areassociated with desmin-related myopathy, a familial cardiac andskeletal myopathy (CSM), and with distal myopathies. [provided byRefSeq].
Background Reference 1:
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Background Reference 2:
van Spaendonck-Zwarts, K., et al. Clin. Genet. (2010) In press :
Background Reference 3:
Zimmerman, R.S., et al. Genet. Med. 12(5):268-278(2010)
Background Reference 4:
Bar, H., et al. J. Mol. Biol. 397(5):1188-1198(2010)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-618

List Size:
400 ul

List Price:

$495.00

Datasheet
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