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Western blot analysis in K562 cell line lysates (35ug/lane).
Western blot analysis in K562 cell line lysates (35ug/lane).

DGCR14 Antibody

CATALOG NUMBER: 57-364

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This DGCR14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 217-244 amino acids from the Central region of human DGCR14.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
53 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
DGCR14
Additional Names:
Protein DGCR14, DiGeorge syndrome critical region 13, DiGeorge syndrome critical region 14, DiGeorge syndrome protein H, DGS-H, Protein ES2, DGCR14, DGCR13, DGSH, DGSI, ES2
Protein Accession Number:
Q96DF8
Protein Gi Number:
27805463
Ncbi Gene Id Number:
8220
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene is located within the minimal DGS criticalregion (MDGCR) thought to contain the gene(s) responsible for agroup of developmental disorders. These disorders include DiGeorgesyndrome, velocardiofacial syndrome, conotruncal anomaly facesyndrome, and some familial or sporadic conotruncal cardiac defectswhich have been associated with microdeletion of 22q11.2. Theencoded protein may be a component of C complex spliceosomes, andthe orthologous protein in the mouse localizes to the nucleus.
Background Reference 1:
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Background Reference 2:
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Background Reference 3:
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Background Reference 4:
Wang, H., et al.Neural Transm 113(10):1551-1561(2006)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-364

List Size:
400 ul

List Price:

$495.00

Datasheet
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