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DLL4 Recombinant Protein

CATALOG NUMBER: 90-154

Specifications
source-species:
HEK293 cells
Species:
Mouse
source-species:
HEK293 cells
Recombinant Protein Sequence:
Signal peptide and extracellular domain of mouse DLL4 (aa 1-532) is fused at the C-terminus to the Fc portion of human IgG1.
Fusion Tag:
Fc Tag
Application Note:
This recombinant proteins is for research use only.
Biological Activity:
Inhibits adipogenesis of 3T3L-1 cells.
Purity:
>90% (SDS-PAGE).

Endotoxin level is less than 0.1EU/ μg purified protein (LAL test; Lonza).
physical-state:
Liquid
Buffer:
0.2um-filtered solution in PBS.
Storage Conditions:
Working aliquots are stable for up to 3 months when stored at -20°C.
Ncbi Official Symbol:
Dll4
Additional Names:
Delta-like Protein 4, Delta4
Protein Accession Number:
Q9JI71
Protein Gi Number:
341940447
Ncbi Gene Id Number:
54485
Background:
The Notch ligand delta-like protein 4 (DLL4) is expressed highly and selectively within the arterial endothelium and has been shown to function as a ligand for Notch1 and Notch4. It is induced by VEGF as a negative feedback regulator and acts to prevent overexuberant angiogenic sprouting, pro-moting the timely formation of a well differentiated vascular network. DLL4-Notch1 signaling regulates the formation of appropriate numbers of tip cells to control vessel sprouting and branching in the mouse retina.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

90-154

List Size:
10 ug

List Price:

$365.00

Datasheet
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