DLX4 Antibody

CATALOG NUMBER: 57-441

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This DLX4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 72-100 amino acids from the Central region of human DLX4.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
26 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
DLX4
Additional Names:
Homeobox protein DLX-4, Beta protein 1, Homeobox protein DLX-7, Homeobox protein DLX-8, DLX4, BP1, DLX7, DLX8, DLX9
Protein Accession Number:
Q92988
Protein Gi Number:
85700416
Ncbi Gene Id Number:
1748
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
Many vertebrate homeo box-containing genes have beenidentified on the basis of their sequence similarity withDrosophila developmental genes. Members of the Dlx gene familycontain a homeobox that is related to that of Distal-less (Dll), agene expressed in the head and limbs of the developing fruit fly.The Distal-less (Dlx) family of genes comprises at least 6different members, DLX1-DLX6. The DLX proteins are postulated toplay a role in forebrain and craniofacial development. Threetranscript variants have been described for this gene, however, thefull length nature of one variant has not been described. Studiesof the two splice variants revealed that one encoded isoformfunctions as a repressor of the beta-globin gene while the otherisoform lacks that function.
Background Reference 1:
Jugessur, A., et al. PLoS ONE(7), E11493 (2010) :
Background Reference 2:
Schwartz, A.M., et al. Mod. Pathol. 22(1):1-6(2009)
Background Reference 3:
Man, Y.G., et al. Cancer Biomark 5(1):9-17(2009)
Background Reference 4:
Cavalli, L.R., et al. Cancer Genet. Cytogenet. 187(1):19-24(2008)

FOR RESEARCH USE ONLY

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Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-441

List Size:
400 ul

List Price:

$495.00

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