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Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).
Western blot analysis in MDA-MB453 cell line lysates (35ug/lane).

DMGDH Antibody

CATALOG NUMBER: 59-586

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This DMGDH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 836-864 amino acids from the C-terminal region of human DMGDH.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
97 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
DMGDH
Additional Names:
Dimethylglycine dehydrogenase, mitochondrial, ME2GLYDH, DMGDH
Protein Accession Number:
Q9UI17
Protein Gi Number:
296434575
Ncbi Gene Id Number:
29958
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
This gene encodes an enzyme involved in the catabolism ofcholine, catalyzing the oxidative demethylation of dimethylglycineto form sarcosine. The enzyme is found as a monomer in themitochondrial matrix, and uses flavin adenine dinucleotide andfolate as cofactors. Mutation in this gene causes dimethylglycinedehydrogenase deficiency, characterized by a fishlike body odor,chronic muscle fatigue, and elevated levels of the muscle form ofcreatine kinase in serum.
Background Reference 1:
Mostowska, A., et al. Eur. J. Oral Sci. 118(4):325-332(2010)
Background Reference 2:
Bailey, S.D., et al. Diabetes Care (2010) In press :
Background Reference 3:
Jugessur, A., et al. PLoS ONE(7), E11493 (2010) :
Background Reference 4:
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

59-586

List Size:
400 ul

List Price:

$495.00

Datasheet
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