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Western blot analysis in K562 cell line lysates (35ug/lane).
Western blot analysis in K562 cell line lysates (35ug/lane).

DNAI1 Antibody

CATALOG NUMBER: 58-705

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Homology:
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Immunogen:
This DNAI1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 92-120 amino acids from the N-terminal region of human DNAI1.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
79 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
DNAI1
Additional Names:
Dynein intermediate chain 1, axonemal, Axonemal dynein intermediate chain 1, DNAI1
Protein Accession Number:
Q9UI46
Protein Gi Number:
12643888
Ncbi Gene Id Number:
27019
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The inner- and outer-arm dyneins, which bridge between thedoublet microtubules in axonemes, are the force-generating proteinsresponsible for the sliding movement in axonemes. The intermediateand light chains, thought to form the base of the dynein arm, helpmediate attachment and may also participate in regulating dyneinactivity. This gene encodes an intermediate chain dynein, belongingto the large family of motor proteins. Mutations in this generesult in abnormal ciliary ultrastructure and function associatedwith primary ciliary dyskinesia (PCD) and Kartagener syndrome.
Background Reference 1:
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 2:
Leigh, M.W., et al. Curr. Opin. Pediatr. 21(3):320-325(2009)
Background Reference 3:
Zuccarello, D., et al. Hum. Reprod. 23(8):1957-1962(2008)
Background Reference 4:
Failly, M., et al. Respiration 76(2):198-204(2008)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

58-705

List Size:
400 ul

List Price:

$495.00

Datasheet
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