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Immobilized Human DNAM-1, Fc Tag at 10 ug/mL (100 ul/well),can bind Human Nectin-2, His Tag with a linear range of 0.08-1.25 ug/mL.
Immobilized Human DNAM-1, Fc Tag at 10 ug/mL (100 ul/well),can bind Human Nectin-2, His Tag with a linear range of 0.08-1.25 ug/mL.

DNAM-1 Recombinant Protein

CATALOG NUMBER: 96-864

Tested Applications:
ELISA, WB
Specifications
source-species:
HEK293 cells
Species:
Human
source-species:
HEK293 cells
Recombinant Protein Sequence:
Glu 19 - Asn 247
Fusion Tag:
Fc Tag
Tested Applications:
ELISA, WB
Application Note:
This recombinant protein can be used for E, WB. For research use only.
Predicted Molecular Weight:
52.6 kDa
Biological Activity:
Measured by its binding ability in a functional ELISA. Immobilized Human DNAM-1, Fc Tag at 10 ug/mL (100 ul/well),can bind Human Nectin-2, His Tag with a linear range of 0.08-1.25 ug/mL.
Purity:
>95% as determined by SDS-PAGE.

Endotoxin level is less than 1.0 EU per ug by the LAL method.
physical-state:
Lyophilized
Buffer:
Tris with Glycine, Arginine and NaCl, pH7.5
Storage Conditions:
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Ncbi Official Symbol:
DNAM-1
Additional Names:
DNAM1,CD226,PTA1
Protein Accession Number:
NP_006557
Ncbi Gene Id Number:
10666
Background:
DNAX accessory molecule 1 (DNAM-1), a single-pass type I membrane protein, is also known as CD226 antigen and platelet and T cell activation antigen 1 (PTA1), which contains 2 Ig-like C2-type (immunoglobulin-like) domains. DNAM-1 is a ~65 kDa glycoprotein expressed on the surface of natural killer cells, platelets, monocytes and a subset of T cells. DNAM-1 mediates cellular adhesion to other cells bearing its ligands, CD112 and CD155, and cross-linking DNAM-1 with antibodies causes cellular activation. Furthermore, DNAM-1 can interact with PVR and PVRL2.
Background Reference 1:
Shibuya A., et al.,1995, Immunity 4:573-581.
Background Reference 2:
Tahara-Hanaoka S., et al .,2003, Int. Immunol. 16:533-538.
Background Reference 3:
Pende D., et al.,2004, Mol. Immunol. 42:463-469.

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

CATALOG NUMBER:

96-864

List Size:
0.1 mg

List Price:

$463.00

Datasheet
Shipping Info

$65 Standard Overnight flat rate for as many products shipped within the United States.

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