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Western blot analysis of Dok5 using rabbit polyclonal Dok5 Antibody (PTB domain) using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the Dok5 gene.
Western blot analysis of Dok5 using rabbit polyclonal Dok5 Antibody (PTB domain) using 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the Dok5 gene.

Dok5 Antibody

CATALOG NUMBER: 56-408

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Human
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Human
Immunogen:
This Dok5 antibody is generated from rabbits immunized with a recombinant protein (GST-tag removed) from human Dok5.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
35 kDa
Purification:
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
DOK5
Additional Names:
Docking protein 5, Downstream of tyrosine kinase 5, Insulin receptor substrate 6, IRS-6, IRS6, DOK5, C20orf180
Protein Accession Number:
Q9P104
Protein Gi Number:
26393190
Ncbi Gene Id Number:
55816
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK5 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of RET in neuronal differentiation.
Background Reference 1:
Liu, X., et al.Am Acad Child Adolesc Psychiatry 49(1):33-41(2010)
Background Reference 2:
Tabassum, R., et al. BMC Med. Genet. 11, 35 (2010) :
Background Reference 3:
Shi, L., et al. Cell. Signal. 18(11):1995-2003(2006)
Background Reference 4:
Cai, D., et al. J. Biol. Chem. 278(28):25323-25330(2003)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

56-408

List Size:
400 ul

List Price:

$495.00

Datasheet
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