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Western blot analysis in mouse spleen tissue lysates (35ug/lane).
Western blot analysis in mouse spleen tissue lysates (35ug/lane).

DOK7 Antibody

CATALOG NUMBER: 57-126

Clonality:
Polyclonal
Tested Applications:
WB
Host Species:
Rabbit
Species Reactivity:
Mouse
Conjugate:
Unconjugated
Specifications
Host Species:
Rabbit
Species Reactivity:
Mouse
Immunogen:
This DOK7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-55 amino acids from the N-terminal region of human DOK7.
Conjugate:
Unconjugated
Tested Applications:
WB
Application Note:
For WB starting dilution is: 1:1000
Predicted Molecular Weight:
53 kDa
Purification:
This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality:
Polyclonal
Isotype:
Rabbit Ig
Physical State:
Liquid
Buffer:
Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration:
batch dependent
Storage Conditions:
Store at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Ncbi Official Symbol:
DOK7
Additional Names:
Protein Dok-7, Downstream of tyrosine kinase 7, DOK7, C4orf25
Protein Accession Number:
Q18PE1
Protein Gi Number:
115311705
Ncbi Gene Id Number:
285489
User Note:
Optimal dilutions for each application to be determined by the researcher.
Background:
The protein encoded by this gene is essential forneuromuscular synaptogenesis. The protein functions in aneuralactivation of muscle-specific receptor kinase, which is requiredfor postsynaptic differentiation, and in the subsequent clusteringof the acetylcholine receptor in myotubes. This protein can alsoinduce autophosphorylation of muscle-specific receptor kinase.Mutations in this gene are a cause of familial limb-girdlemyasthenia autosomal recessive, which is also known as congenitalmyasthenic syndrome type 1B. Alternative splicing results inmultiple transcript variants.
Background Reference 1:
Bergamin, E., et al. Mol. Cell 39(1):100-109(2010)
Background Reference 2:
Srour, M., et al. Neuromuscul. Disord. 20(7):453-457(2010)
Background Reference 3:
Maselli, R.A., et al. Hum. Mol. Genet. 19(12):2370-2379(2010)
Background Reference 4:
Ben Ammar, A., et al. J. Neurol. 257(5):754-766(2010)

FOR RESEARCH USE ONLY

For additional information, visit ProSci’s Terms & Conditions Page.

Disclaimer:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

CATALOG NUMBER:

57-126

List Size:
400 ul

List Price:

$495.00

Datasheet
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